职称：教授，博导
单位：复旦大学
部门：生命科学学院
职务：无
出生年月：1982年9月，性别：男
社会职务：无
联系方式：wangleiwanglei@fudan.edu.cn 
微博：无

研究领域：
       人类生殖疾病的遗传学基础。利用分子遗传学手段寻找相关疾病致病基因，并利用细胞，动物模型对相关基因功能展开深入研究。近五年，发现了相关疾病的一系列新致病基因并进行了致病机制的研究。以通讯作者在N Engl J Med, Am J Hum Genet等国际期刊上发表SCI论文20篇，影响因子总计超过150。发现了首个基因突变导致人类卵子成熟障碍并揭示了其致病的分子机制，研究发表于国际顶级杂志NEJM上（NEJM，2016），NEJM杂志同期配发了专题评论，认为这是认识卵子成熟障碍机理迈出的第一步。

论文与著作：
(1) Biaobang Chen*, Zhihua Zhang*, Xiaoxi Sun*, Yanping Kuang*, Xiaoyan Mao*, Xueqian Wang*, Zheng Yan, Bin Li, Yao Xu, Min Yu, Jing Fu, Jian Mu, Zhou Zhou, Qiaoli Li, Li Jin, Lin He, Qing Sang# and Lei Wang#. Biallelic mutations in PATL2 cause female infertility characterized by oocyte maturation arrest.Am J Hum Genet, 2017，Oct 5;101(4):609-615 (#Corresponding author)
(2) Ruizhi Feng*, Qing Sang*, Yanping Kuang*, Xiaoxi Sun*，Zheng Yan*, Shaozhen Zhang*, Juanzi Shi, Guoling Tian, Anna Luchniak, Yusuke Fukuda, Bin Li, Min Yu, Junling Chen,Yao Xu, Luo Guo, Ronggui Qu, Xueqian Wang, Zhaogui Sun, Miao Liu, Huijuan Shi, Hongyan Wang, Yi Feng, Ruijin Shao, Renjie Chai, Qiaoli Li, Qinghe Xing, Rui Zhang, Eva Nogales, Li Jin, Lin He, Mohan L. Gupta, Jr., Nicholas J. Cowan# and Lei Wang#. Mutations in TUBB8 and Human oocyte meiotic arrest. NEJM. 2016; 374:223-32. (#Corresponding author) (#Corresponding author)
(3) Yao Xu*, Yingli Shi*, Min Yu*, Jing Fu*, Ruizhi Feng, Qing Sang, Bo Liang, Biaobang Chen, Ronggui Qu, Bin Li, Zheng Yan, Xiaoyan Mao, Yanping Kuang, Li Jin, Lin He, Xiaoxi Sun# and Lei Wang#. Mutations in PADI6 causes female infertility characterized by early embryonic arrest. Am J Hum Genet. 2016, Sep 1;99(3):744-52. (#Corresponding author)
(4) Ruizhi Feng, Zheng Yan, Bin Li, Min Yu, Qing Sang, Guoling Tian，Yao Xu , Biaobang Chen, Ronggui Qu, Zhaogui Sun, Xiaoxi Sun, Li Jin, Lin He, Yanping Kuang, Nicholas J. Cowan and Lei Wang*. Mutations in TUBB8 cause a multiplicity of phenotype in human oocytes and early embryos. J Med Genet 2016, Oct;53(10):662-71. (*Corresponding author) (Cover Story) (*Corresponding author)
(5) Sang Q, Zhang J, Feng R, Wang X, Li Q, Zhao X, Xing Q, Chen W, Du J, Sun S, Chai R, Liu D, Jin L, He L, Li H*, Wang L*. Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42. Hum Mol Genet. 2014 Dec 1;23(23):6201-11. (*Corresponding author)
(6) Sang Q, Yao Z, Wang H, Feng R, Wang H, Zhao X, Xing Q, Jin L, He L, Wu L*, Wang L*. Identification of microRNAs in human follicular fluid: characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary syndrome in vivo.   J Clin Endocrinol Metab. 2013 Jul;98 (7):3068-3079 (*Corresponding author) (This paper is awarded as International Award for publishing Excellence in JCEM in 2013)

荣誉与奖励：

• 2015年 以第一完成人身份获全国妇幼健康科技奖自然科学奖二等奖
• 2016年 获教育部长江学者奖励计划-青年长江学者
• 2017年 获国家杰出青年科学基金
• 2017年 获科技部中青年科技创新领军人才
• 2017年 以第一完成人身份获全国妇幼健康科技奖自然科学奖一等奖
• 2019年 入选国家“万人”计划领军人才